AVP Enterprise AI Architecture and Strategy

Philadelphia, PA, US Mid Level AI Architect

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About This Role

AI job market dashboard showing open roles by category

Description

Penn Medicine is dedicated to our tripartite mission of providing the highest level of care to patients, conducting innovative research, and educating future leaders in the field of medicine. Working for this leading academic medical center means collaboration with top clinical, technical and business professionals across all disciplines.

Today at Penn Medicine, someone will make a breakthrough. Someone will heal a heart, deliver hopeful news, and give comfort and reassurance. Our employees shape our future each day. Are you living your life's work? Entity: Corporate Services

Department: Enterprise Technology Architecture and Strategy

Location: 3535 Market St

Summary:

  • Reporting to the VP, Enterprise Technology Architecture and Strategy, the Associate Vice President (AVP), Enterprise AI Architecture and Strategy is the leadership role responsible for defining, governing, and advancing the organization's enterprise wide AI and Gen AI strategy and architecture within a complex, highly regulated healthcare environment.
  • This role serves as the enterprise leader for AI technology strategy, architecture, and governance, accountable for aligning AI vision, roadmap, standards, and operating model with organizational strategy across clinical care, research, academic, and operation domains. The AVP ensures AI technology investments are clinically safe, ethically sound, secure, scalable, and compliant, while enabling innovation that improves patient outcomes, operational efficiency, and institutional performance.
  • The AVP leads Enterprise AI Architecture and Strategy practice as a core component of Enterprise Architecture, owning multi\-year AI technology strategy and architecture roadmaps, reference architectures, and governance frameworks. In close partnership with executive leadership, clinical informatics, digital health, data, security, privacy, legal, compliance, and risk management teams, the AVP balances innovation velocity with patient safety, regulatory obligations, and enterprise resilience, ensuring responsible and sustainable adoption of AI at scale.

Responsibilities:

  • Defines and owns the enterprise AI technology strategy, ensuring alignment with healthcare, clinical, research, and business strategies
  • Builds a high performing AI architecture team
  • Sets performance expectations, develops talent, and ensures organizational maturity and succession readiness
  • Develops and executes a multi\-year enterprise AI architecture and strategy roadmap aligned to investment planning and value realization
  • Establishes enterprise standards and reference architectures for:
  • + AI/ML and GenAI platforms

+ Agentic AI Orchestration, agent framework, and multi\-agent ecosystems

+ AI monitoring, observability, and performance management

+ LLM model lifecycle management (development, validation, deployment, monitoring, retirement)

+ Integration with EHRs, clinical systems, research platforms, and enterprise applications

+ Monitoring and observability

  • Oversee AI and GenAI governance, including architecture review, model risk management, clinical safety considerations, and ethical AI practices
  • Partners with Information Security, Privacy, Legal, Compliance, Clinical Informatics, and Risk Management to ensure compliance with: HIPAA and healthcare data privacy, AI related regulations, accreditation, and audit requirements
  • Provide enterprise direction, expectations, and guardrails for how AI must behave, be governed, and be trusted, especially where AI affects patients, clinicians, research, or regulated decisions.
  • Represents Enterprise Architecture in AI investment decisions, portfolio governance, and executive steering committees
  • Defines and tracks architecture KPIs, communicating outcomes, risks, and value realization to senior executive leadership.
  • Serves as an internal and external thought leader for enterprise and healthcare AI strategy and architecture

Credentials:

  • Certified Machine Learning, Professional ML Engineer, AI Governance, or equivalent AI certification is preferred.

Education or Equivalent Experience:

  • Bachelor's degree is required.
  • 15\+ years of Information Technology (IT) experience, with 7\+ years Enterprise Architecture Leadership is required.
  • 3\+ years AI Enterprise Architect \& Strategy is required.

We believe that the best care for our patients starts with the best care for our employees. Our employee benefits programs help our employees get healthy and stay healthy. We offer a comprehensive compensation and benefits program that includes one of the finest prepaid tuition assistance programs in the region. Penn Medicine employees are actively engaged and committed to our mission. Together we will continue to make medical advances that help people live longer, healthier lives.

Live Your Life's Work

We are an Equal Opportunity employer. Candidates are considered for employment without regard to race, ethnicity, color, sex, sexual orientation, gender identity, religion, national origin, ancestry, age, disability, marital status, familial status, genetic information, domestic or sexual violence victim status, citizenship status, military status, status as a protected veteran or any other status protected by applicable law.

Role Details

Company Penn Medicine
Title AVP Enterprise AI Architecture and Strategy
Location Philadelphia, PA, US
Category AI Architect
Experience Mid Level
Salary Not disclosed
Remote No

About This Role

This role sits at the intersection of AI and engineering, building systems that bring machine learning capabilities into production environments. The scope varies by company, but the common thread is applying AI technology to solve real business problems at scale. Most AI roles today require a combination of software engineering fundamentals and domain-specific ML knowledge, with the exact mix depending on the team's maturity and the product they're building.

The AI job market is evolving fast. New role categories emerge as companies figure out what they need to ship AI-powered products. What matters most is the ability to learn quickly, build working systems, and iterate based on real-world performance data. The specific title matters less than the skills you bring and the problems you can solve. Companies are past the experimentation phase and want engineers who can deliver production-quality systems that work reliably at scale.

Across the 4,317 AI roles we're tracking, AI Architect positions make up 1% of the market. At Penn Medicine, this role fits into their broader AI and engineering organization.

AI hiring keeps growing across industries. Companies in tech, finance, healthcare, and retail are all building AI teams. The strongest demand is for people who can bridge the gap between AI research and production engineering. The shift toward generative AI has created new role types (LLM Engineer, Prompt Engineer, AI Agent Developer) that didn't exist three years ago, while traditional roles (Data Scientist, ML Engineer) have evolved to incorporate LLM capabilities.

What the Work Looks Like

Day-to-day work involves a mix of building, debugging, and collaborating. You'll write code, review pull requests, participate in design discussions, and work with cross-functional teams (product, design, data) to define what AI features should do and how they should behave. Expect to spend time on both technical implementation and communication. Most AI teams operate in two-week sprint cycles, with regular demos and retrospectives. The ratio of heads-down coding to meetings and reviews varies by seniority, with senior roles spending more time on architecture decisions and mentorship.

AI hiring keeps growing across industries. Companies in tech, finance, healthcare, and retail are all building AI teams. The strongest demand is for people who can bridge the gap between AI research and production engineering. The shift toward generative AI has created new role types (LLM Engineer, Prompt Engineer, AI Agent Developer) that didn't exist three years ago, while traditional roles (Data Scientist, ML Engineer) have evolved to incorporate LLM capabilities.

Skills in Demand for This Role

Python (52% of roles) Aws (28% of roles) Azure (22% of roles) Rag (21% of roles) Gcp (15% of roles) Pytorch (15% of roles) Prompt Engineering (14% of roles) Kubernetes (13% of roles)

Python and cloud platform experience are common requirements. Specific skill needs vary by company and focus area, but familiarity with ML frameworks, data pipelines, and API design covers the basics for most roles. RAG (Retrieval-Augmented Generation), vector databases, and LLM API integration are increasingly standard requirements across role types.

Beyond the core stack, communication skills matter more than many technical candidates realize. The ability to explain AI capabilities and limitations to non-technical stakeholders is a differentiator at every level. Technical writing, documentation, and clear thinking about tradeoffs are underrated skills in AI roles. Experience with evaluation methodology (how to measure whether an AI system is working well) is becoming a core requirement, especially for roles that involve LLM integration.

Look for job postings that specify the problems you'll work on, the tech stack, and the team structure. Vague postings that list every AI buzzword are often a sign the company hasn't figured out what they need. Strong postings describe the product context, the team you'd join, and the specific challenges you'd tackle.

Compensation Benchmarks

AI Architect roles pay a median of $237,300 based on 102 positions with disclosed compensation. Mid-level AI roles across all categories have a median of $194,400.

Across all AI roles, the market median is $215,000. Top-quartile compensation starts at $266,300. The 90th percentile reaches $320,790. For comparison, the highest-paying categories include AI Safety ($287,500) and Research Engineer ($272,100). By seniority level: Entry: $110,000; Mid: $194,400; Senior: $227,400; Director: $274,554; VP: $241,000.

Penn Medicine AI Hiring

Penn Medicine has 1 open AI role right now. They're hiring across AI Architect. Based in Philadelphia, PA, US.

Location Context

Across all AI roles, 15% (635 positions) offer remote work, while 3,657 require on-site attendance. Top AI hiring metros: New York (1,650 roles, $220,000 median); San Francisco (1,335 roles, $265,000 median); Los Angeles (708 roles, $214,112 median).

Career Path

Common paths into AI Architect roles include Software Engineer, Data Scientist, Data Analyst.

From here, career progression typically leads toward Senior Engineer, AI Architect, Engineering Manager, Principal Engineer.

Focus on building things that work. A deployed project that solves a real problem is worth more than any certification. Contribute to open-source, build portfolio projects, and invest in fundamentals (software engineering, statistics, systems design) rather than chasing the latest framework. The AI field moves fast, but the engineers who succeed long-term are the ones with strong fundamentals who can adapt to new tools and paradigms as they emerge.

What to Expect in Interviews

AI interviews typically combine coding challenges (Python-focused), system design questions tailored to the role, and discussions about your experience with relevant tools and frameworks. Strong candidates demonstrate both technical depth and the ability to make pragmatic engineering tradeoffs. Prepare portfolio projects that demonstrate end-to-end capability rather than isolated skills.

When evaluating opportunities: Look for job postings that specify the problems you'll work on, the tech stack, and the team structure. Vague postings that list every AI buzzword are often a sign the company hasn't figured out what they need. Strong postings describe the product context, the team you'd join, and the specific challenges you'd tackle.

AI Hiring Overview

The AI job market has 4,317 open positions tracked in our dataset. By seniority: 138 entry-level, 2,071 mid-level, 1,655 senior, and 453 leadership roles (Director, VP, C-Level). Remote roles make up 15% of the market (635 positions). The remaining 3,657 roles require on-site or hybrid attendance.

The market median for AI roles is $215,000. Top-quartile compensation starts at $266,300. The 90th percentile reaches $320,790. Highest-paying categories: AI Safety ($287,500 median, 34 roles); Research Engineer ($272,100 median, 227 roles); AI Engineering Manager ($244,000 median, 23 roles).

AI hiring keeps growing across industries. Companies in tech, finance, healthcare, and retail are all building AI teams. The strongest demand is for people who can bridge the gap between AI research and production engineering. The shift toward generative AI has created new role types (LLM Engineer, Prompt Engineer, AI Agent Developer) that didn't exist three years ago, while traditional roles (Data Scientist, ML Engineer) have evolved to incorporate LLM capabilities.

The AI Job Market Today

The AI job market spans 4,317 open positions across 15 role categories. The largest categories by volume: AI/ML Engineer (3,004), Data Scientist (345), AI Software Engineer (309). These three account for the majority of open positions, though smaller categories often have higher per-role compensation because of specialized skill requirements.

The seniority mix tells a story about where AI teams are in their maturity. Entry-level roles (138) are outnumbered by mid-level (2,071) and senior (1,655) positions, reflecting that most companies are past the 'build a team from scratch' phase and need experienced engineers who can ship production systems. Leadership roles (Director, VP, C-Level) total 453 positions, representing the bottleneck between technical execution and organizational strategy.

Remote work availability sits at 15% of all AI roles (635 positions), with 3,657 requiring on-site or hybrid attendance. The remote share has stabilized after the post-pandemic correction. Senior and specialized roles (Research Scientist, ML Architect) are more likely to be remote-eligible than entry-level positions, partly because experienced hires have more negotiating power and partly because these roles require less hands-on mentorship.

AI compensation is structured in clear tiers. The market median sits at $215,000. Top-quartile roles start at $266,300, and the 90th percentile reaches $320,790. These figures include base salary with disclosed compensation. Total compensation (including equity, bonuses, and sign-on) runs 20-40% higher at companies that offer those components.

Category matters for compensation. AI Safety roles lead at $287,500 median, while Prompt Engineer roles sit at $145,000. The spread between highest and lowest-paying categories reflects the premium on specialized technical skills versus broader analytical roles.

The most in-demand skills across all AI postings: Python (2,249 postings), Aws (1,224 postings), Azure (938 postings), Rag (915 postings), Gcp (660 postings), Pytorch (640 postings), Prompt Engineering (624 postings), Kubernetes (559 postings). Python dominates, appearing in the vast majority of role descriptions regardless of category. Cloud platform experience (AWS, GCP, Azure) is the second most common requirement. The newer entrants to the top skills list (RAG, vector databases, LLM APIs) reflect the shift from traditional ML toward generative AI applications.

Frequently Asked Questions

Based on 102 roles with disclosed compensation, the median salary for AI Architect positions is $237,300. Actual compensation varies by seniority, location, and company stage.
Python and cloud platform experience are common requirements. Specific skill needs vary by company and focus area, but familiarity with ML frameworks, data pipelines, and API design covers the basics for most roles. RAG (Retrieval-Augmented Generation), vector databases, and LLM API integration are increasingly standard requirements across role types.
About 15% of the 4,317 AI roles we track offer remote work. Remote availability varies by company and seniority level, with senior and leadership roles more likely to offer location flexibility.
Penn Medicine is among the companies actively hiring for AI and ML talent. Check our company profiles for detailed breakdowns of open roles, salary ranges, and hiring trends.
Common next steps from AI Architect positions include Senior Engineer, AI Architect, Engineering Manager, Principal Engineer. Progression depends on whether you lean toward technical depth, people management, or product strategy.

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