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About This Role
About Anthropic
Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems.
About the role
As an Applied AI Engineer on the Startups team at Anthropic, you will be a trusted technical advisor to the top AI-native life sciences and biotech startups as they grow from early product to scale. Some of these companies build products on Claude that they sell to the rest of the industry, and others do the science themselves and want Claude woven into how their own research runs, and this role works with both. You'll lead deep technical engagements, partnering directly with startup engineering and scientific teams to help them build their products on Claude and run their own research with it, advising on implementation and agent design as they build what is newly possible with AI in the life sciences. You will bridge the gap between what Claude can do and what the life sciences need, working alongside some of the strongest teams in the field on problems that matter and pushing the boundaries of AI in science as you go.
Working closely with Applied AI Architects, Account Executives, and Anthropic's Product, Engineering, and Research teams, you'll help startups build at the edge of what is possible with Claude. You'll leverage your AI engineering expertise and your scientific domain knowledge to develop custom evaluation frameworks, design scalable architectures, and create the technical resources that enable life sciences startups to succeed with Claude.
Responsibilities
- Serve as a deep technical advisor to high-potential life sciences and biotech startups, whether Claude sits inside the product they sell or inside the way they make discoveries, working alongside them to build innovative use cases that push the boundaries of AI in scientific research and development
- Work hands-on with startup engineering teams and their scientists through pair programming and architecture reviews that accelerate their development, and understand their scientific workflows end to end so that your guidance fits into real research pipelines
- Develop prototypes and technical documentation, including evaluation suites, scientifically grounded benchmarks, AI engineering techniques, and architecture diagrams, that enable startups to build, operate, and scale with Claude
- Create reference implementations and sample code that many companies can adopt without starting from scratch, such as example MCP servers for domain-specific data sources like genomics platforms, literature databases, and experimental repositories, along with agent skills for common scientific workflows
- Collaborate closely with Applied AI Architects to maintain context and continuity across customer engagements
- Identify patterns across engagements, including what is hard about deploying AI in the life sciences such as heterogeneous data, auditability requirements, and the gap between a working prototype and a system that scientists trust, and contribute insights back to Product, Engineering, Research, and the broader Applied AI team, including feedback on the model capabilities and product features that would most accelerate discovery work
- Create technical content for startup audiences including documentation, tutorials, and sample code
- Represent Anthropic across the life sciences startup ecosystem and foster community engagement through hackathons, webinars, technical office hours, in-person founder events, and research show and tells
- Travel to customer sites for workshops, implementation guidance, and relationship building
You may be a good fit if you have
- Deep experience in the life sciences or biotech, gained through research or industry work in areas such as genomics, drug discovery, molecular design, lab automation, or clinical development, along with strong opinions of your own about how to bridge the gap between what AI can do today and what the life sciences need
- 4+ years of technical experience as a software engineer, ML or research engineer, computational biologist, research scientist, or technical founder, with either production experience building LLM-powered applications, including prompting, context engineering, agent architectures, evaluation frameworks, and deployment at scale, or a track record of successfully applying AI to real scientific work in the lab or in research
- Experience with startups or high-growth companies and a love of working with founders and small teams that move quickly
- Strong technical communication skills, with the ability to translate complex AI concepts into architectural decisions and actionable implementation plans for both engineering and scientific audiences and to run technical workshops, hackathons, or developer-focused events
- A collaborative approach to working across teams, the ability to context-switch across scientific domains and use cases, and a passion for making powerful technology safe and beneficial
The annual compensation range for this role is listed below.
For sales roles, the range provided is the role’s On Target Earnings ("OTE") range, meaning that the range includes both the sales commissions/sales bonuses target and annual base salary for the role.
Annual Salary:
$280,000 - $320,000 USD
Logistics
Minimum education: Bachelor’s degree or an equivalent combination of education, training, and/or experience
Required field of study: A field relevant to the role as demonstrated through coursework, training, or professional experience
Minimum years of experience: Years of experience required will correlate with the internal job level requirements for the position
Location-based hybrid policy: Currently, we expect all staff to be in one of our offices at least 25% of the time. However, some roles may require more time in our offices.
Visa sponsorship: We do sponsor visas! However, we aren't able to successfully sponsor visas for every role and every candidate. But if we make you an offer, we will make every reasonable effort to get you a visa, and we retain an immigration lawyer to help with this.
We encourage you to apply even if you do not believe you meet every single qualification. Not all strong candidates will meet every single qualification as listed. Research shows that people who identify as being from underrepresented groups are more prone to experiencing imposter syndrome and doubting the strength of their candidacy, so we urge you not to exclude yourself prematurely and to submit an application if you're interested in this work. We think AI systems like the ones we're building have enormous social and ethical implications. We think this makes representation even more important, and we strive to include a range of diverse perspectives on our team.
Your safety matters to us. To protect yourself from potential scams, remember that Anthropic recruiters only contact you from @anthropic.com email addresses. In some cases, we may partner with vetted recruiting agencies who will identify themselves as working on behalf of Anthropic. Be cautious of emails from other domains. Legitimate Anthropic recruiters will never ask for money, fees, or banking information before your first day. If you're ever unsure about a communication, don't click any links—visit anthropic.com/careers directly for confirmed position openings.
How we're different
We believe that the highest-impact AI research will be big science. At Anthropic we work as a single cohesive team on just a few large-scale research efforts. And we value impact — advancing our long-term goals of steerable, trustworthy AI — rather than work on smaller and more specific puzzles. We view AI research as an empirical science, which has as much in common with physics and biology as with traditional efforts in computer science. We're an extremely collaborative group, and we host frequent research discussions to ensure that we are pursuing the highest-impact work at any given time. As such, we greatly value communication skills.
The easiest way to understand our research directions is to read our recent research. This research continues many of the directions our team worked on prior to Anthropic, including: GPT-3, Circuit-Based Interpretability, Multimodal Neurons, Scaling Laws, AI & Compute, Concrete Problems in AI Safety, and Learning from Human Preferences.
Come work with us!
Anthropic is a public benefit corporation headquartered in San Francisco. We offer competitive compensation and benefits, optional equity donation matching, generous vacation and parental leave, flexible working hours, and a lovely office space in which to collaborate with colleagues. Guidance on Candidates' AI Usage: Learn about our policy for using AI in our application process.
Salary Context
This $280K-$320K range is above the 75th percentile for AI/ML Engineer roles in our dataset (median: $178K across 2239 roles with salary data).
View full AI/ML Engineer salary data →Role Details
About This Role
AI/ML Engineers build and deploy machine learning models in production. They work across the full ML lifecycle: data pipelines, model training, evaluation, and serving infrastructure. The role has evolved significantly over the past two years. Where ML Engineers once spent most of their time on model architecture, the job now tilts heavily toward inference optimization, cost management, and integrating LLM capabilities into existing systems. Companies want engineers who can ship production systems, and the experimenter-only role is fading fast.
Day-to-day, you're writing training pipelines, debugging data quality issues, setting up evaluation frameworks, and figuring out why your model performs differently in staging than it did on your dev set. The best ML engineers are obsessive about reproducibility and measurement. They instrument everything. They know that a model is only as good as the data feeding it and the infrastructure serving it.
Across the 11,520 AI roles we're tracking, AI/ML Engineer positions make up 76% of the market. At Anthropic, this role fits into their broader AI and engineering organization.
Demand for AI/ML Engineers has been strong and consistent. Unlike some AI roles that spike with hype cycles, ML engineering is a foundational need. Every company deploying AI models needs people who can keep them running, and the gap between research prototypes and production systems keeps growing.
What the Work Looks Like
A typical week might include: debugging a data pipeline that's silently dropping 3% of training examples, running A/B tests on a new model version, writing documentation for a feature flag system that lets you roll back model deployments, and reviewing a junior engineer's PR for a new evaluation metric. Meetings tend to be cross-functional since ML touches product, engineering, and data teams.
Demand for AI/ML Engineers has been strong and consistent. Unlike some AI roles that spike with hype cycles, ML engineering is a foundational need. Every company deploying AI models needs people who can keep them running, and the gap between research prototypes and production systems keeps growing.
Skills Required
Python and PyTorch dominate the requirements. Most roles expect experience with cloud platforms (AWS, GCP, or Azure) and familiarity with ML frameworks like TensorFlow or JAX. RAG (Retrieval-Augmented Generation) has become a top-3 skill requirement as companies integrate LLMs into their products. Docker and Kubernetes show up in about a third of postings, reflecting the production focus of the role.
Beyond the core stack, employers increasingly want experience with experiment tracking tools (MLflow, Weights & Biases), feature stores, and vector databases. Fine-tuning experience is valuable but less common than you'd think from reading Twitter. Most production LLM work is RAG and prompt engineering, not fine-tuning. If you have both, you're in a strong position.
Companies that are serious about AI/ML hiring tend to post specific infrastructure details in the job description: the frameworks they use, their model serving stack, their data pipeline tools. Vague postings that just say 'ML experience required' without specifics are often companies that haven't figured out what they need yet.
Compensation Benchmarks
AI/ML Engineer roles pay a median of $212,040 based on 13,780 positions with disclosed compensation. Mid-level AI roles across all categories have a median of $193,200. This role's midpoint ($300K) sits 41% above the category median. Disclosed range: $280K to $320K.
Across all AI roles, the market median is $213,480. Top-quartile compensation starts at $264,000. The 90th percentile reaches $318,400. For comparison, the highest-paying categories include AI Safety ($266,050) and AI Engineering Manager ($253,461). By seniority level: Entry: $112,320; Mid: $193,200; Senior: $230,000; Director: $272,250; VP: $235,830.
Anthropic AI Hiring
Anthropic has 57 open AI roles right now. They're hiring across AI/ML Engineer, Research Engineer, AI Architect, AI Product Manager. Positions span San Francisco, CA, US, New York, NY, Seattle, WA. Compensation range: $4K - $850K.
Location Context
AI roles in San Francisco pay a median of $260,550 across 2,766 tracked positions. That's 22% above the national median.
Career Path
Common paths into AI/ML Engineer roles include Data Scientist, Software Engineer, Research Engineer.
From here, career progression typically leads toward ML Architect, AI Engineering Manager, Principal ML Engineer.
The fastest path into ML engineering is through software engineering with a self-directed ML education. A CS degree helps, but production engineering skills matter more than academic credentials. Build something that works, deploy it, and measure it. That portfolio project is worth more than a Coursera certificate. For career growth, the fork comes around the senior level: go deep on technical complexity (staff/principal track) or move into managing ML teams.
What to Expect in Interviews
Expect system design questions around ML pipelines: how you'd build a training pipeline for a specific use case, handle data drift, or design A/B testing infrastructure for model deployments. Coding rounds typically involve Python, with emphasis on data manipulation (pandas, numpy) and algorithm implementation. Take-home assignments often ask you to build an end-to-end ML pipeline from raw data to deployed model.
When evaluating opportunities: Companies that are serious about AI/ML hiring tend to post specific infrastructure details in the job description: the frameworks they use, their model serving stack, their data pipeline tools. Vague postings that just say 'ML experience required' without specifics are often companies that haven't figured out what they need yet.
AI Hiring Overview
The AI job market has 11,520 open positions tracked in our dataset. By seniority: 140 entry-level, 5,630 mid-level, 4,176 senior, and 1,574 leadership roles (Director, VP, C-Level). Remote roles make up 6% of the market (708 positions). The remaining 10,737 roles require on-site or hybrid attendance.
The market median for AI roles is $213,480. Top-quartile compensation starts at $264,000. The 90th percentile reaches $318,400. Highest-paying categories: AI Safety ($266,050 median, 70 roles); AI Engineering Manager ($253,461 median, 58 roles); Research Engineer ($252,000 median, 476 roles).
Demand for AI/ML Engineers has been strong and consistent. Unlike some AI roles that spike with hype cycles, ML engineering is a foundational need. Every company deploying AI models needs people who can keep them running, and the gap between research prototypes and production systems keeps growing.
The AI Job Market Today
The AI job market spans 11,520 open positions across 16 role categories. The largest categories by volume: AI/ML Engineer (8,769), AI Software Engineer (586), AI Product Manager (511). These three account for the majority of open positions, though smaller categories often have higher per-role compensation because of specialized skill requirements.
The seniority mix tells a story about where AI teams are in their maturity. Entry-level roles (140) are outnumbered by mid-level (5,630) and senior (4,176) positions, reflecting that most companies are past the 'build a team from scratch' phase and need experienced engineers who can ship production systems. Leadership roles (Director, VP, C-Level) total 1,574 positions, representing the bottleneck between technical execution and organizational strategy.
Remote work availability sits at 6% of all AI roles (708 positions), with 10,737 requiring on-site or hybrid attendance. The remote share has stabilized after the post-pandemic correction. Senior and specialized roles (Research Scientist, ML Architect) are more likely to be remote-eligible than entry-level positions, partly because experienced hires have more negotiating power and partly because these roles require less hands-on mentorship.
AI compensation is structured in clear tiers. The market median sits at $213,480. Top-quartile roles start at $264,000, and the 90th percentile reaches $318,400. These figures include base salary with disclosed compensation. Total compensation (including equity, bonuses, and sign-on) runs 20-40% higher at companies that offer those components.
Category matters for compensation. AI Safety roles lead at $266,050 median, while Prompt Engineer roles sit at $140,000. The spread between highest and lowest-paying categories reflects the premium on specialized technical skills versus broader analytical roles.
The most in-demand skills across all AI postings: Python (2,267 postings), Aws (1,178 postings), Azure (972 postings), Rag (924 postings), Gcp (715 postings), Pytorch (586 postings), Claude (572 postings), Kubernetes (559 postings). Python dominates, appearing in the vast majority of role descriptions regardless of category. Cloud platform experience (AWS, GCP, Azure) is the second most common requirement. The newer entrants to the top skills list (RAG, vector databases, LLM APIs) reflect the shift from traditional ML toward generative AI applications.
Frequently Asked Questions
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