Applied AI Engineer, Beneficial Deployments (Life Sciences)

$280K - $320K San Francisco, CA, US Mid Level AI/ML Engineer

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Skills & Technologies

AnthropicClaude

About This Role

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About Anthropic

Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems.

About Beneficial Deployments:

Beneficial Deployments ensures AI reaches and benefits the communities that need it most. We partner with nonprofits, foundations, and mission-driven organizations to deploy Claude in education, global health, economic mobility, and life sciences — focusing on raising the floor for those who need it most.

About the Role:

We're looking for an Applied AI Engineer to join our Beneficial Deployments team, focused on maximizing the impact of Claude in the life sciences. Our goal is ambitious: accelerate scientific progress from R&D through translation by an order of magnitude. That means making Claude the go-to tool for the life sciences ecosystem from early discovery in academia to paradigm shifting biotech to reimaging pharma pipelines — and building the technical infrastructure to back that up.

You'll work directly with flagship research partners like Howard Hughes Medical Institute and The Allen Institute, embedded in their scientific workflows. This isn't consulting from the outside — you'll be building alongside their engineers, prototyping agents that fit into real research pipelines, and developing the ecosystem-level tooling (MCP servers, benchmarks, reusable agent skills) that extends Claude's usefulness across the broader life sciences community. This role will be part of the founding Beneficial Deployments applied AI team focused on bringing more of life sciences closer to the frontier and be responsible for building with our partners.

Responsibilities:

  • Partner deeply with flagship life sciences research institutions — understand their scientific workflows end-to-end, build hands-on with their engineering teams, and help take projects from early exploration to production systems integrated into how they do science day-to-day.
  • Develop reusable ecosystem infrastructure, like MCP servers for domain-specific data sources (genomics platforms, literature databases, experimental repositories), instruments, scientifically-grounded benchmarks, and agent skills that other institutions can adopt without starting from scratch.
  • Identify what's actually hard about deploying AI in life sciences (heterogeneous data, auditability requirements, the prototype-to-trust gap) and feed those findings back to product, engineering, and research.
  • Create technical content and documentation that lets partners self-serve, so what works for one institution can scale globally without the same level of hand-holding.

You Might Be a Good Fit If You Have:

  • 4+ years as a Software Engineer, Forward Deployed Engineer, or technical founder — with production experience shipping systems that real users depend on.
  • Deep research experience in life sciences, biomedical research, or scientific computing. Bonus if you've studied genomics, neuroscience, or drug discovery specifically and are comfortable getting deeply technical with academics.
  • Experience building LLM-powered tools or applications: prompting, context engineering, agent architectures, evaluation frameworks.
  • Builder credibility from shipping production code as a software engineer, forward-deployed engineer, or technical founder.
  • A scrappy mentality–comfortable wearing multiple hats, building from scratch, driving clarity in ambiguous situations, and doing whatever it takes to further the mission.

The annual compensation range for this role is listed below.

For sales roles, the range provided is the role’s On Target Earnings ("OTE") range, meaning that the range includes both the sales commissions/sales bonuses target and annual base salary for the role.

Annual Salary:

$280,000 - $320,000 USD

Logistics

Minimum education: Bachelor’s degree or an equivalent combination of education, training, and/or experience

Required field of study: A field relevant to the role as demonstrated through coursework, training, or professional experience

Minimum years of experience: Years of experience required will correlate with the internal job level requirements for the position

Location-based hybrid policy: Currently, we expect all staff to be in one of our offices at least 25% of the time. However, some roles may require more time in our offices.

Visa sponsorship: We do sponsor visas! However, we aren't able to successfully sponsor visas for every role and every candidate. But if we make you an offer, we will make every reasonable effort to get you a visa, and we retain an immigration lawyer to help with this.

We encourage you to apply even if you do not believe you meet every single qualification. Not all strong candidates will meet every single qualification as listed. Research shows that people who identify as being from underrepresented groups are more prone to experiencing imposter syndrome and doubting the strength of their candidacy, so we urge you not to exclude yourself prematurely and to submit an application if you're interested in this work. We think AI systems like the ones we're building have enormous social and ethical implications. We think this makes representation even more important, and we strive to include a range of diverse perspectives on our team.

Your safety matters to us. To protect yourself from potential scams, remember that Anthropic recruiters only contact you from @anthropic.com email addresses. In some cases, we may partner with vetted recruiting agencies who will identify themselves as working on behalf of Anthropic. Be cautious of emails from other domains. Legitimate Anthropic recruiters will never ask for money, fees, or banking information before your first day. If you're ever unsure about a communication, don't click any links—visit anthropic.com/careers directly for confirmed position openings.

How we're different

We believe that the highest-impact AI research will be big science. At Anthropic we work as a single cohesive team on just a few large-scale research efforts. And we value impact — advancing our long-term goals of steerable, trustworthy AI — rather than work on smaller and more specific puzzles. We view AI research as an empirical science, which has as much in common with physics and biology as with traditional efforts in computer science. We're an extremely collaborative group, and we host frequent research discussions to ensure that we are pursuing the highest-impact work at any given time. As such, we greatly value communication skills.

The easiest way to understand our research directions is to read our recent research. This research continues many of the directions our team worked on prior to Anthropic, including: GPT-3, Circuit-Based Interpretability, Multimodal Neurons, Scaling Laws, AI & Compute, Concrete Problems in AI Safety, and Learning from Human Preferences.

Come work with us!

Anthropic is a public benefit corporation headquartered in San Francisco. We offer competitive compensation and benefits, optional equity donation matching, generous vacation and parental leave, flexible working hours, and a lovely office space in which to collaborate with colleagues. Guidance on Candidates' AI Usage: Learn about our policy for using AI in our application process.

Salary Context

This $280K-$320K range is above the 75th percentile for AI/ML Engineer roles in our dataset (median: $176K across 1540 roles with salary data).

View full AI/ML Engineer salary data →

Role Details

Company Anthropic
Title Applied AI Engineer, Beneficial Deployments (Life Sciences)
Location San Francisco, CA, US
Category AI/ML Engineer
Experience Mid Level
Salary $280K - $320K
Remote No

About This Role

AI/ML Engineers build and deploy machine learning models in production. They work across the full ML lifecycle: data pipelines, model training, evaluation, and serving infrastructure. The role has evolved significantly over the past two years. Where ML Engineers once spent most of their time on model architecture, the job now tilts heavily toward inference optimization, cost management, and integrating LLM capabilities into existing systems. Companies want engineers who can ship production systems, and the experimenter-only role is fading fast.

Day-to-day, you're writing training pipelines, debugging data quality issues, setting up evaluation frameworks, and figuring out why your model performs differently in staging than it did on your dev set. The best ML engineers are obsessive about reproducibility and measurement. They instrument everything. They know that a model is only as good as the data feeding it and the infrastructure serving it.

Across the 9,653 AI roles we're tracking, AI/ML Engineer positions make up 76% of the market. At Anthropic, this role fits into their broader AI and engineering organization.

Demand for AI/ML Engineers has been strong and consistent. Unlike some AI roles that spike with hype cycles, ML engineering is a foundational need. Every company deploying AI models needs people who can keep them running, and the gap between research prototypes and production systems keeps growing.

What the Work Looks Like

A typical week might include: debugging a data pipeline that's silently dropping 3% of training examples, running A/B tests on a new model version, writing documentation for a feature flag system that lets you roll back model deployments, and reviewing a junior engineer's PR for a new evaluation metric. Meetings tend to be cross-functional since ML touches product, engineering, and data teams.

Demand for AI/ML Engineers has been strong and consistent. Unlike some AI roles that spike with hype cycles, ML engineering is a foundational need. Every company deploying AI models needs people who can keep them running, and the gap between research prototypes and production systems keeps growing.

Skills Required

Anthropic (2% of roles) Claude (4% of roles)

Python and PyTorch dominate the requirements. Most roles expect experience with cloud platforms (AWS, GCP, or Azure) and familiarity with ML frameworks like TensorFlow or JAX. RAG (Retrieval-Augmented Generation) has become a top-3 skill requirement as companies integrate LLMs into their products. Docker and Kubernetes show up in about a third of postings, reflecting the production focus of the role.

Beyond the core stack, employers increasingly want experience with experiment tracking tools (MLflow, Weights & Biases), feature stores, and vector databases. Fine-tuning experience is valuable but less common than you'd think from reading Twitter. Most production LLM work is RAG and prompt engineering, not fine-tuning. If you have both, you're in a strong position.

Companies that are serious about AI/ML hiring tend to post specific infrastructure details in the job description: the frameworks they use, their model serving stack, their data pipeline tools. Vague postings that just say 'ML experience required' without specifics are often companies that haven't figured out what they need yet.

Compensation Benchmarks

AI/ML Engineer roles pay a median of $212,000 based on 11,857 positions with disclosed compensation. Mid-level AI roles across all categories have a median of $193,200. This role's midpoint ($300K) sits 42% above the category median. Disclosed range: $280K to $320K.

Across all AI roles, the market median is $213,400. Top-quartile compensation starts at $264,230. The 90th percentile reaches $319,400. For comparison, the highest-paying categories include AI Safety ($253,100) and Research Engineer ($252,000). By seniority level: Entry: $110,408; Mid: $193,200; Senior: $228,700; Director: $272,275; VP: $235,000.

Anthropic AI Hiring

Anthropic has 52 open AI roles right now. They're hiring across AI Software Engineer, AI Engineering Manager, AI/ML Engineer, Research Engineer. Positions span New York, NY, US, San Francisco, CA, US, Washington, DC, US. Compensation range: $315K - $850K.

Location Context

AI roles in San Francisco pay a median of $264,500 across 2,413 tracked positions. That's 24% above the national median.

Career Path

Common paths into AI/ML Engineer roles include Data Scientist, Software Engineer, Research Engineer.

From here, career progression typically leads toward ML Architect, AI Engineering Manager, Principal ML Engineer.

The fastest path into ML engineering is through software engineering with a self-directed ML education. A CS degree helps, but production engineering skills matter more than academic credentials. Build something that works, deploy it, and measure it. That portfolio project is worth more than a Coursera certificate. For career growth, the fork comes around the senior level: go deep on technical complexity (staff/principal track) or move into managing ML teams.

What to Expect in Interviews

Expect system design questions around ML pipelines: how you'd build a training pipeline for a specific use case, handle data drift, or design A/B testing infrastructure for model deployments. Coding rounds typically involve Python, with emphasis on data manipulation (pandas, numpy) and algorithm implementation. Take-home assignments often ask you to build an end-to-end ML pipeline from raw data to deployed model.

When evaluating opportunities: Companies that are serious about AI/ML hiring tend to post specific infrastructure details in the job description: the frameworks they use, their model serving stack, their data pipeline tools. Vague postings that just say 'ML experience required' without specifics are often companies that haven't figured out what they need yet.

AI Hiring Overview

The AI job market has 9,653 open positions tracked in our dataset. By seniority: 193 entry-level, 4,500 mid-level, 3,455 senior, and 1,505 leadership roles (Director, VP, C-Level). Remote roles make up 6% of the market (568 positions). The remaining 9,010 roles require on-site or hybrid attendance.

The market median for AI roles is $213,400. Top-quartile compensation starts at $264,230. The 90th percentile reaches $319,400. Highest-paying categories: AI Safety ($253,100 median, 57 roles); Research Engineer ($252,000 median, 419 roles); AI Engineering Manager ($251,622 median, 51 roles).

Demand for AI/ML Engineers has been strong and consistent. Unlike some AI roles that spike with hype cycles, ML engineering is a foundational need. Every company deploying AI models needs people who can keep them running, and the gap between research prototypes and production systems keeps growing.

The AI Job Market Today

The AI job market spans 9,653 open positions across 16 role categories. The largest categories by volume: AI/ML Engineer (7,301), Data Scientist (441), AI Software Engineer (438). These three account for the majority of open positions, though smaller categories often have higher per-role compensation because of specialized skill requirements.

The seniority mix tells a story about where AI teams are in their maturity. Entry-level roles (193) are outnumbered by mid-level (4,500) and senior (3,455) positions, reflecting that most companies are past the 'build a team from scratch' phase and need experienced engineers who can ship production systems. Leadership roles (Director, VP, C-Level) total 1,505 positions, representing the bottleneck between technical execution and organizational strategy.

Remote work availability sits at 6% of all AI roles (568 positions), with 9,010 requiring on-site or hybrid attendance. The remote share has stabilized after the post-pandemic correction. Senior and specialized roles (Research Scientist, ML Architect) are more likely to be remote-eligible than entry-level positions, partly because experienced hires have more negotiating power and partly because these roles require less hands-on mentorship.

AI compensation is structured in clear tiers. The market median sits at $213,400. Top-quartile roles start at $264,230, and the 90th percentile reaches $319,400. These figures include base salary with disclosed compensation. Total compensation (including equity, bonuses, and sign-on) runs 20-40% higher at companies that offer those components.

Category matters for compensation. AI Safety roles lead at $253,100 median, while Prompt Engineer roles sit at $141,440. The spread between highest and lowest-paying categories reflects the premium on specialized technical skills versus broader analytical roles.

The most in-demand skills across all AI postings: Python (1,605 postings), Aws (916 postings), Azure (724 postings), Rag (634 postings), Gcp (522 postings), Pytorch (495 postings), Kubernetes (384 postings), Claude (383 postings). Python dominates, appearing in the vast majority of role descriptions regardless of category. Cloud platform experience (AWS, GCP, Azure) is the second most common requirement. The newer entrants to the top skills list (RAG, vector databases, LLM APIs) reflect the shift from traditional ML toward generative AI applications.

Frequently Asked Questions

Based on 11,857 roles with disclosed compensation, the median salary for AI/ML Engineer positions is $212,000. Actual compensation varies by seniority, location, and company stage.
Python and PyTorch dominate the requirements. Most roles expect experience with cloud platforms (AWS, GCP, or Azure) and familiarity with ML frameworks like TensorFlow or JAX. RAG (Retrieval-Augmented Generation) has become a top-3 skill requirement as companies integrate LLMs into their products. Docker and Kubernetes show up in about a third of postings, reflecting the production focus of the role.
About 6% of the 9,653 AI roles we track offer remote work. Remote availability varies by company and seniority level, with senior and leadership roles more likely to offer location flexibility.
Anthropic is among the companies actively hiring for AI and ML talent. Check our company profiles for detailed breakdowns of open roles, salary ranges, and hiring trends.
Common next steps from AI/ML Engineer positions include ML Architect, AI Engineering Manager, Principal ML Engineer. Progression depends on whether you lean toward technical depth, people management, or product strategy.

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